Nationales Referenzzentrum
für Surveillance
von nosokomialen Infektionen
NRZ
 
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A. Introduction
The object of this page is to enable English speaking users to access German Nosocomial Infection Surveillance System (KISS) reference data.
In 1997 we initiated a nationwide nosocomial infection surveillance system so as to create a database for hospital infections throughout Germany, "KISS" being an acronym for "Krankenhaus-(=Hospital)-Infektions-Surveillance-System". The number of hospitals participating has since been increasing continuously.

B. General principles
Participation is on a voluntary basis and individual results from each hospital are handled strictly confidentially. Before embarking on surveillance staff have to attend an introductory course and then participate in subsequent annual meetings in which the experiences of other hospitals are discussed.
The participating hospitals receive their own standardized and stratified infection rates on a regular basis in order to be able to compare this data with data from the national data pool fed in by all the other hospitals participating. Once a year a meeting of these hospitals is organized for the discussion of methodological points and exchanging the participants' experience with using such data for infection control.
In the majority of hospitals infection control personnel are responsible for recording data and dispatching it to the KISS data centre.

C. Surveillance components
The definitions and methods can be traced back to the U.S. National Nosocomial Infection Surveillance (NNIS) system with, however, some modifications. For instance, different surveillance components have self-contained surveillance protocols, each focused on a particular group of patients. These protocols are unfortunately not yet available in English. Every hospital participating in KISS chooses one or more components. Up till now the following components have been established:

C1. ICU surveillance component (= "ITS-KISS")
This component focuses on lower respiratory tract infections (pneumonia and bronchitis), blood stream and urinary tract infections in intensive care units. National reference data are generated for device associated infection rates. This surveillance component is unit based.

C2. Surgical patient surveillance component (= "OP-KISS")
The surveillance of surgical site infections (SSI) is concentrated in about 20 operative procedure categories (= "Indikator-Operationen"), which may differ from NNIS categories. Voluntarily participating surgical departments select those procedures they wish to follow up from the KISS operative procedure list. This surveillance component is patient based.

Infection rates are stratified according to the NNIS system.
A risk point is attributed to patients if

  • the patient's general condition, as measured by the ASA score, is 3 or worse,
  • the wound contamination class is classified as contaminated or dirty/infected,
  • the operation lasted longer than 75 % of all other operations of the same type. (i.e., the cut-off time is calculated in minutes from the actual German data instead of using the NNIS cut-off time)
    These three factors are considered as being of equal significance. The NNIS risk index score ranges from 0 to 3, that is the number of risk points.

KISS operative procedure category list (= "Liste der Indikator-OP"):
Most of the KISS operative procedure categories are identical to NNIS procedure categories or differ only in detail, however, some procedures don't correspond to NNIS. The KISS operative procedure categories are defined by their OPS-301-codes, which is a specific German modification of the WHO's ICPM-procedure codes. The following are the operative procedures with the highest participation rates, for which reference data are published on the web twice yearly:
The entire list (with OPS-301-codes) in German is shown here:
OP-LISTE

Operative procedure category
Code (KISS)
corresponding NNIS code
Appendectomy
APPE
APPY
Knee arthroscopy
ART
-
Cholecystectomy (only fully endoscopically performed operations)
CHOL E
CHOL
Cholecystectomy (operations with laparatomy)
CHOL K
CHOL
Colon surgery
COLO
COLO
Coronary artery bypass
with a graft harvested from an extremity
COBY L
CBGB
Coronary artery bypass
with chest incision only
COBY T
CBGC
Vascular surgery
GC
VS
Herniorrhaphy
HERN
HER
Hip prosthesis (only procedures from orthopaedic departments, i.e. mostly elective surgery)
HPRO O
HPRO
Hip prosthesis (only procedures from traumatology departments, i.e. mostly indicated by trauma)
HPRO T
HPRO
Abdominal hysterectomy
HYST
HYST
Knee prosthesis
KPRO
KPRO
Mastectomy
MAST
MAST
Nephrectomy
NEPH
NEPH
Talocrural joint operation
OSG
-
Hip fracture without joint replacement
OSHF
-
Prostatectomy
PRST
PRST
Caesarean section
SECC
CSEC
Stripping of varicose veins
STRIP
-
Thyroidectomy (strumectomy)
STRUM
-

C3. Neonatal ICU component (= "NEO-KISS")
Surveillance is restricted to very low birth weight infants (<1500 g) and includes pneumonia, blood stream infection and necrotizing enterocolitis (NEC). The number of device days (central / peripheral vascular catheter, mechanical ventilation / CPAP) and days with antibiotic treatment are registered for every patient.


D. How to find current reference data on the web
First go to the homepage www.nrz-hygiene.de (Deutsche Version), then to SURVEILLANCE and choose the surveillance component (as described above). The reference data at the bottom of the page are in PDF files called "Referenzdaten" .
Current reference data ICU component: ITS-KISS Referenz
Current reference data SSI component: OP-KISS Referenz
Current reference data NICU component: NEO-KISS Referenz

E. German - English glossary
The purpose of this chapter is to help the user to understand the most recent reference data, which is published twice a year on the website. A translation and short explanation are given for each surveillance component in the order of occurrence in the German reference data files:

E1. ICU component (= "ITS-KISS")

Art der Intensivstation
ICUs are stratified in ICU types as follows:
chirurgisch
surgical
interdisziplinär
medical-surgical (mostly in smaller hospitals with only one ICU and where patients from different specialist medical departments are treated)
medizinisch
medical
neurochirurgisch
neurosurgical
pädiatrisch
paediatric (ICU for children no longer of neonatal age, surveillance for neonatal ICUs is performed in a special component: NEO-KISS)
Anzahl der Intensivstationen
number of participating ICUs
Anzahl der Beobachtungsmonate
number of months under observation
Anzahl Patienten
number of patients included
Anzahl Patiententage
number of patient days included
Liegedauer (Tage)
average length of stay in the ICU in days

Device-Anwendungsraten
über alle Intensivstationen dieser Art
device utilisation ratio
for all ICU's of this type
HWK = Harnwegkatheter
urinary catheter
ZVK = zentral-venöser (oder -arterieller) Katheter
central venous/arterial catheter
Beatmung
mechanical ventilation
Anzahl Devicetage
number of device days
gepoolte Device-Anwendungsrate
pooled mean device utilisation ratios

Device-assoziierte Infektionsraten
über alle Intensivstationen dieser Art
device associated infection
for all ICU's of this type
Harnweginfektion*
urinary tract infection (UTI)
Sepsis
primary bloodstream infection
Pneumonie
pneumonia
Bronchitis
bronchitis (only those ICUs are considered in the denominator data, which have diagnosed at least one bronchitis, because not all ICUs distinguish pneumonia and bronchitis within lower respiratory tract infections.
Anzahl Devicetage
number of device days
Anzahl nosokomialer Infektionen
number of nosocomial infections (i.e., device associated)
Device-assoziierte nosokomiale Infektionsrate
rate of device associated nosocomial infections

* denominator data for UTI: ICUs are stratified in those with (="mit") and without (="ohne") routine urine screening for bacteria. The latter ones perform microbiological exams of urine only when clinically indicated.

E.2 SSI component (= OP-KISS)

Referenzdaten für chirurgische Abteilungen
reference data for surgical departments
Anzahl Abteilungen
number of operating departments participating
Operationsart
Operative procedure category (see separate list in section C2). These categories may be not identical with NNIS operative procedure categories
Risikokategorie
NNIS risk index category
Anzahl
number
gepoolte Wundinfektionsrate
pooled arithmetical mean surgical site infection rate (of all hospitals)
Wundinfektionen
surgical site infections (SSI)
Wundinfektionsart

type of surgical site infections (SSI), defined by the CDC criteria:

  • A1 = superficial
  • A2 = deep incisional
  • A3 = organ/space
Verteilung der standardisierten Wundinfektionsraten der Abteilungen (SIR)
distribution of the departments standardized SSI rate (SIR). The SIR is calculated in the following way: the number of cases of SSI in a given hospital is divided by the number of SSI cases, already expected for this hospital and based on the risk index distribution among that hospital's patients.
OP-Dauer (in Minuten)
cut off point for the duration of the operation (in minutes). If the patient's operation lasts for longer than this, a risk point is attributed. This cut off time represents the 75th percentile of the operations of the same type. (i.e., the cut-off time is calculated in minutes from the actual German data instead of using the NNIS cut-off time) and is recalculated every 6 month.
Wundklassifikation
wound contamination class
(1 clean, 2 clean-contaminated,
3 contaminated, 4 dirty-infected)
Erklärung

explanation:

  • Only hospitals performing at least 30 operation surveillances for each type are included in the reference data.
  • The number "-999" in a list means that this value is non-defined (i.e., calculation by zero error)


E3. Neo-KISS = component for neonatal ICUs (NICUs):
Surveillance is concentrated on very low birth weight (VLBW) neonates (<1500 g birth weight). These neonates are under surveillance for infections until they have reached a weight of
1800 g.
The results are stratified in 3 birth weight groups
(= "Geburtsgewichtsklasse"):up to (= "bis") 499g, 500 to (="bis") 999 g, 1000 to (="bis") 1499 g.

Anzahl Abteilungen
number of participating NICUs participating
Anzahl Patienten
number of patients included
Anzahl Patiententage zu erfassten Antibiotikatagen
number of patient days (denominator) and days with antibiotic treatment
Mittlere Liegedauer (Tage)
average length of stay on the NICU in days
gepoolte Wundinfektionsrate
pooled arithmetical mean surgical site infection rate (of all hospitals)

Device-Anwendungsraten
(über alle Patienten in dieser Geburtsgewichtsklasse)
device utilisation ratio
(throughout all patients of this birth weight group):
Devices
devices
ZVK = zentral-venöse (oder -arterieller) Katheter
central venous/arterial catheter
PVK = peripher venöser Katheter
peripheral venous catheter
Tubus
invasive mechanical ventilation
CPAP
non-invasivly administered continuous positive airway pressure [CPAP]
Antibiotika
antibiotics
Anzahl Device-Tage
number of device days
gepoolte Device-Anwendungsrate
pooled mean device utilisation ratios

Inzidenzdichten und Device-assozierte Infektionsraten
(über alle Patienten in dieser Geburtsgewichtsklasse)
device associated infection rates
(throughout all patients of this birth weight group)
Sepsis
blood stream infection
Pneumonie
pneumonia
NEC
necrotizing enterocolitis
Anzahl Infektionen
number of infections (i.e. device associated and not device associated)
Inzidenzdichte
incidence density (= no. of infections no. of patient days x 1000)
Antibiotika
antibiotics
Anzahl Device-ass. Infektionen
number of device associated infections
Device-assoziierte Infektionsrate
rate of device associated infections (= no. of device associated infections no. of device days x 1000)


F. References in English:

1. Gastmeier P, Sohr D, Just HM, Nassauer A, Daschner F and Rüden H. How to survey nosocomial infections. Infect Control Hosp Epidemiol 2000;21:366-370

2. Gastmeier P, Sohr D, Geffers C, Nassauer A, Daschner F and Rüden H. Are nosocomial infection rates in intensive care units useful benchmark parameters? Infection 2000;28:346-350

3. Geffers C, Gastmeier P, Bräuer H, Daschner F and Rüden H. Surveillance of nosocomial infections in ICUs: is post discharge surveillance indispensable? Infect Control Hosp Epidemiol 2001;22:157-159

4. Coello R, Gastmeier P and de Boer AS. Surveillance of hospital acquired infection in England, Germany and The Netherlands: will international comparison of rates be possible? Infect Control Hosp Epidemiol 2001;22:393-397

5. Gastmeier P, Sohr D, Geffers C, Nassauer A, Dettenkofer M and Rüden H. Occurrence of methicillin resistant Staphylococcus aureus infections in German intensive care units. Infection 2002;30:198-202

Contact:
You may contact us by email in English for any further questions. nrz@charite.de

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Institut für Umweltmedizin und Krankenhaushygiene - UK Freiburg
Institut für Umweltmedizin und Krankenhaushygiene - UK Freiburg
Kooperationspartner

 

Institut für Medizinische Mikrobiologie und Krankenhaushygiene - MHH
Institut für Medizinische Mikrobiologie und Krankenhaushygiene - Medizinische Hochschule Hannover Kooperationspartner

 

© 2005 Nationales Referenzzentrum für Surveillance von nosokomialen Infektionen